Work

Grading Melanocytic Dysplasia: Updated Histopathologic Criteria

Year: 2024

Type: article

Abstract: Dr. Martin C. Mihm, Jr.'s innovative work on the dysplastic nevus achieved a milestone in his chapter in the World Health Organisation Classification of Skin Tumours (WHO-C). WHO-C presents a dichotomous classification (high-grade versus low-grade dysplastic nevi) and a quantitative metric to assess melanocytic nuclear enlargement. The Duke classification is a related approach that provides mostly quantitative histopathologic criteria for dysplastic nevi and gives due weight to architectural features as well as cytology. This paper proposes and illustrates updated criteria for scoring and grading melanocytic dysplasia, incorporating some of the definitions and categories of WHO-C, while refining the quantitative and architectural elements of the Duke grading system to facilitate more detailed and precise assessment of dysplastic nevi.

Source: Journal of Cutaneous Pathology

DOI: 10.1111/cup.14744

Authors: Christopher R. Shea, Victor G. Prieto, Catherine M. Shachaf, Scott R. Florell

Institutions: University of Chicago, University of Chicago Medical Center, The University of Texas MD Anderson Cancer Center, University of Utah, University of Utah Health Care

Language: English

Topic: Cutaneous Melanoma Detection and Management

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,400