Work

The Effects of Carbonate on Candida albicans Filamentation, Biofilm Formation, and Antifungal Resistance

Year: 2024

Type: article

Abstract: Candida albicans, a member of the normal microbial population of healthy humans, is an opportunistic pathogen that can cause serious disease in immunocompromised patients. An important virulence factor of C. albicans is the formation of biofilms. These organized communities of cells are efficient at attaching to host cells and implanted medical devices. Carbonate has been studied as an agricultural antifungal agent, and here we demonstrate that carbonate can affect filamentation, biofilm formation, and antifungal drug resistance in C. albicans.

Source: MicrobiologyOpen

DOI: 10.1002/mbo3.70008

Authors: Trenton P. Miedema, Kayla E. Grooters, Ian A. Cleary

Institutions: Grand Valley State University, Western Michigan University

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,370