Synthesis of 4‐Cyclobutene‐Isoquinolines From Aryl Imidates by Ru(II)‐Catalyzed Domino C–H Activation/Cyclization
Year: 2024
Type: article
Abstract: ABSTRACT A highly regioselective approach for constructing 4‐cyclobutene‐isoquinoline derivatives through ruthenium‐catalyzed domino C–H activation/cyclization of aryl imidates has been demonstrated. This new transformation tolerates various substituted functional groups on imidates and propargylic monofluoroalkynes, resulting in the corresponding products being delivered in moderate yields.
Source: Applied Organometallic Chemistry
DOI: 10.1002/aoc.7896
Authors: Min Wang, Lei Gao, Maozhong Miao, Qianshou Zong, Fei Ling, Jinzhong Yao, Hongwei Zhou
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
Award: 1,3-硫-硼偶极体系促进的类卡宾及其在合成中应用研究
OpenAlex ID: W4404362932