Work

Catalytic Enantioselective Functionalization of Maleimides: An Update

Year: 2024
Type: article
Abstract: Comprehensive Summary Maleimide derivatives are well‐established reactive intermediates also found in natural products, synthetic pharmaceuticals and functional polymers. Their specific reactivity found widespread applications in the field of bioconjugation and allowed for the development of highly selective functionalizations based on simple additions and cycloadditions with the possible control of central and C–N axial chirality. These multisite‐reactive scaffolds have aroused a long‐standing interest throughout the scientific community more particularly as powerful electrophilic partners and more recently as nucleophilic partners in some specific transformations. The persistent interest in these easily accessible synthetic platforms over the last decade has enabled the development of new enantioselective transformations and the major advancements in this field are presented in this review. Key Scientists
Language: English
Field: Chemistry
Open Access status: hybrid
Estimated APC paid: $3,140
OpenAlex ID: W4404366016
FWCI: 1.535
Cites: 118
Cited by: 11
Related to: 10