Work

Chemical diversity of cyanobacterial natural products

Year: 2024

Type: article

Abstract: Covering: 2010 to 2023Cyanobacterial natural products are a diverse group of molecules with promising biotechnological applications. This review examines the chemical diversity of 995 cyanobacterial metabolites reported from 2010 to 2023. A computational analysis using similarity networking was applied to visualize the chemical space and to compare the diversity of cyanobacterial metabolites among taxonomic orders and environmental sources. Key examples are highlighted, detailing their sources, biological activities, and discovery processes.

Source: Natural Product Reports

DOI: 10.1039/d4np00040d

Authors: Márcio B. Weiss, Ricardo M. Borges, Peter Sullivan, João P. B. Domingues, Francisco H. S. da Silva, Victória G. S. Trindade, Shangwen Luo, Jimmy Orjala, Camila M. Crnkovic

Institutions: Universidade de São Paulo, Universidade Federal do Rio de Janeiro, Helmholtz Institute for Pharmaceutical Research Saarland, Saarland University, State Key Laboratory of Applied Organic Chemistry, Lanzhou University, University of Illinois Chicago

Language: English

Topic: Microbial Natural Products and Biosynthesis

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

Open Access status: green

Funders: Fundação de Amparo à Pesquisa do Estado de São Paulo, National Natural Science Foundation of China, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, National Cancer Institute

Awards: G1094275380, The role of Chemistry in holobiont adaptation, Biotechnological prospection of natural products from cyanobacteria, Integrated strategies for natural product discovery from Brazilian cyanobacteria, G5788948360, G75528187, Discovery of Anticancer Agents of Diverse Natural Origin

OpenAlex ID: W4404377250

FWCI: 6.588

Cites: 395

Cited by: 28

Related to: 10