Year: 2024
Type: article
Abstract: Quinoline Schiff bases are a distinct category of chemical compounds that show potential anticancer characteristics due to their unique structural flexibility.The present study investigates how these compounds interact with several types of cancer, with a specific emphasis on understanding how structures affect their effectiveness.Important structures in this group have effects such as insertion into DNA, generating reactive oxygen species (ROS), triggering cell death, and blocking enzyme activity, all of which hinder the growth of cancer cells.Analysing structure-activity relationships (SAR) helps identify changes in the structure that enhance effectiveness and specificity while reducing harm.Future research will explore new delivery methods and enhancements to increase the availability and effectiveness of treatment.Overall, quinoline Schiff bases represent promising scaffolds for the development of next-generation anticancer drugs.
Authors: Gandhi Mansi K., Dr. Shashi V. Ranga
Institution: Gujarat Technological University
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W4404387536