Parvovirus infection in adults: a series of case reports in post-pandemic period
Year: 2024
Type: article
Study design: Case Report
Abstract: Parvovirus infection in immunocompetent patients usually has a mild or asymptomatic course, but some cases may be characterized by a complicated course that requires hospitalization. The aim of our work was the characterization of clinical course of parvovirus infection in immunocompetent patients who required hospitalization. The article discussed three clinical cases of infection caused by human parvovirus B19. Our patients had a pronounced general intoxication syndrome with fever, severe anemia, hepatitis with moderate biochemical activity, and splenomegaly in the first clinical case; erythema multiforme, severe thrombocytopenia and leukopenia in the second clinical case; pericarditis with purple rash in the third clinical case. Patients with immunosuppression could have chronic anemia, pancytopenia, myocarditis, pneumonitis, hepatitis, meningitis, and encephalitis in a course of parvovirus infection. HIV infection was ruled out for all our patients; however, these patients were routinely recommended to undergo additional examinations in order to rule out other possible causes of immunosuppression. Clinical vigilance regarding parvovirus infection is currently relevant, and complex specific diagnostics (serological, immunoblotting and Polymerase Chain Reaction assays) are available and cоuld be used in diagnostic cases to determine the tactics of further examination and treatment. Keywords: parvovirus B19, anemia, thrombocytopenia, leukopenia, hepatitis, pericarditis.
Source: Medicine Today and Tomorrow
Authors: L. Kondratiuk, O. Bezrodna
Institution: Bogomolets National Medical University
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4404400866