Rheumatic Immune-Related Adverse Events With Anti-cyclic Citrullinated Peptide Positivity and Cutaneous Adverse Drug Reactions: A Case Report
Year: 2024
Type: article
Study design: Case Report
Abstract: We report the case of a patient who experienced rheumatic immune-related adverse events (irAEs) with anti-cyclic citrullinated peptide (anti-CCP) positivity and cutaneous adverse drug reactions. A 59-year-old woman with malignant melanoma who was treated with nivolumab as postoperative adjuvant therapy developed polyarthralgia with anti-CCP positivity and dermatologic adverse events caused by celecoxib or lansoprazole. Her rheumatic and cutaneous symptoms greatly improved with oral glucocorticoid treatment. The findings of this case suggest that after treatment with immune checkpoint inhibitors, it is necessary to pay attention to irAEs and provide appropriate treatment.
Source: Cureus
DOI: 10.7759/cureus.73774
Authors: Akiko Yamazaki, Eiji Nakano, Tomohiko Yoshida
Institution: National Cancer Center Hospital
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4404409500