Work

Mechanism of protofibril formation in aqueous collagen solutions

Year: 2024

Type: article

Abstract: The shear viscosity of aqueous collagen solutions was experimentally investigated over the temperature range of 303–353 K and collagen concentrations of 1–7 wt. %. A structural phase transition was observed at ∼315 K, corresponding to the onset of protofibril formation. It is shown that below this temperature, protofibrils containing both ordered and disordered segments are formed, with the proportion of ordered segments increasing as the temperature decreases, reaching ∼30% at 303 K. An analysis of the temperature dependence of the order parameter for the structural transition in the water–collagen system suggests that this transition exhibits characteristics of a second-order phase transition.

Source: AIP Advances

DOI: 10.1063/5.0238555

Authors: Leonid A. Bulavin, Kostyantyn V. Cherevko, Oleksii V. Khorolskyi, Oksana S. Svechnikova, Yurii F. Zabashta

Institutions: Taras Shevchenko National University of Kyiv, Institute for Safety Problems of Nuclear Power Plants, Poltava V.G. Korolenko National Pedagogical University

Language: English

Topic: Collagen: Extraction and Characterization

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,350

OpenAlex ID: W4404415436

FWCI: 0.169

Cites: 43

Cited by: 2

Related to: 10