Work

Persistence diagrams for exploring the shape variability of abdominal aortic aneurysms

Year: 2024

Type: article

Abstract: Abdominal aortic aneurysm consists of a permanent dilation in the abdominal portion of the aorta and, along with its associated pathologies like calcifications and intraluminal thrombi, is one of the most important pathologies of the circulatory system. The shape of the aorta is among the primary drivers for these health issues, with particular reference to all the characteristics which affect the hemodynamics. Starting from the computed tomography angiography of a patient, we propose to summarize such information using tools derived from Topological Data Analysis, obtaining persistence diagrams which describe the irregularities of the lumen of the aorta. We showcase the effectiveness of such shape-related descriptors with a series of supervised and unsupervised case studies.

Source: Scientific Reports

DOI: 10.1038/s41598-024-78301-w

Authors: Dario Arnaldo Domanin, Matteo Pegoraro, Santi Trimarchi, Maurizio Domanin, Piercesare Secchi

Institutions: Aalborg University, University of Milan, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Politecnico di Milano

Language: English

Topic: Topological and Geometric Data Analysis

Subfield: Computational Theory and Mathematics

Field: Computer Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,590