Work

Abemaciclib and Letrozole in Metastatic Male Breast Cancer

Year: 2024

Type: article

Abstract: BACKGROUND: Male breast cancer is a very rare disease and only accounts for around 1% of all breast cancers. The treatment strategies are based on those used for breast cancer in women. So far, there is a lack of randomized data to support specific treatment modalities in men. To our knowledge, a therapeutic approach with a combination of letrozole and abemaciclib has not yet been described for a male patient with metastatic breast cancer. CASE DESCRIPTION: Here, we report a case of a male patient with advanced metastatic breast cancer treated with a combination of letrozole and abemaciclib. The therapy was well tolerated with no reported side effects. The follow-up CT showed regression of the primary tumor mass and the lymph nodes and soft tissue metastases. CONCLUSION: In summary, this case report clearly shows the effectiveness of the therapeutic approach and should be discussed for the treatment of future patients.

Source: Cancer Reports

DOI: 10.1002/cnr2.70054

Authors: Leon Schönfeld, Christian Möhring, Rouven Strobel, Hanns Leonhard Kaatsch, Stephan Waldeck, Ulrike Wagner

Institutions: Bundeswehrzentralkrankenhaus Koblenz, Bundeswehr

Language: English

Topic: Male Breast Health Studies

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,970