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Diagnostic and Therapeutic Challenges of Focal Cortical Dysplasia in Mali: A Case Report

Year: 2024
Type: article
Study design: Case Report
Abstract: Focal Cortical Dysplasias (FCDs) are a common cause of pharmaco-resistant epilepsy. FCDs are rare conditions, and their pathogenesis remains poorly understood. We report a 12-year-old patient seen in our clinic for focal onset epileptic seizures. Neurological examination and brain CT-scan were nearly normal. However, an electroencephalogram (EEG) revealed a slightly slow background rhythm with slow spikes in the medial and right parietal regions and a brain magnetic resonance imaging (MRI) showed a focal cortical thickening in the right parietal lobe with FLAIR hypersignal, indicating a focal cortical dysplasia. Ongoing seizures marked the disease course under antiepileptic polytherapy after 15 months of treatment. Keywords: Focal cortical dysplasia, pharmaco-resistant epilepsy, Mali, Africa.
Authors: Faculté de Médecine et d’Odontostomatologie, USTTB, Bamako, Mali, A Yalcouyé, M Diakité, Pédiatrie, Polyclinique Alliance Médicale, Bamako, Mali, L Cissé, Faculté de Médecine et d’Odontostomatologie, USTTB, Bamako, Mali, SO Djimdé, ME Dembélé, Faculté de Médecine et d’Odontostomatologie, USTTB, Bamako, Mali, AM Koné, Clinique Khaïdara, Bamako, Mali, H Samir, Faculté de Médecine et d’Odontostomatologie, USTTB, Bamako, Mali, CO Guinto, Faculté de Médecine et d’Odontostomatologie, USTTB, Bamako, Mali, G Landouré, Faculté de Médecine et d’Odontostomatologie, USTTB, Bamako, Mali
Language: English
Field: Medicine
Open Access status: bronze
OpenAlex ID: W4404449442
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