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Molecular investigate of slim and adhesion genes of "Staphylococcus saprophyticus" isolated from pregnant women with asymptomatic bacteriuria in Thi-Qar governorates

Year: 2024
Type: article
Abstract: OBJECTIVE: Aims: to investigate and compared the frequency of biof i lm formation ica A and adhesion genes clf A, cnaA, fnbA and fnbB in chromosome and plasmid of S. saprophyticus. PATIENTS AND METHODS: Materials and methods: 48 isolates about S. saprophyticus were selective randomly from total 1019 isolated from pregnant women with asymptomatic bacteriuria where the samples were collected in AL Habboby Hospital and Al-Hussein teaching, and bent Al-Huda hospitals from the fi rst of April 2022 until the fi rst of September 2023 and bacteria of study were identif i ed depend on previous method. RESULTS: Results: PCR appeared, higher existence percentage of study virulence factors genes was in chromosome that reached 399.9% of study bacteria, more than in its in plasmid 66.5%, however the frequency rate of study genes in chromosome was as following: ica A and fnb A genes were complete, 100% (48/48), while cna A and clf A genes percentage were identical and came in second grade that arrived signif i cant rate 83.3% (40/48), the lowest results were showed 33.3% (16/48) isolates harbored fnb B gene, while they were decreased in its plasmid as following: ica A and fnb A genes were 12.5% (6/48) and 22.9% (11/48) respectively, the cna A and clf A genes percentage 6.2 % (3/48) and 4.1% (2/48) respectively, fnb B gene 20.8% (10/48). CONCLUSION: Conclusions: Depend on above data may be ica A, fnb A, clf A, cna A genes more occurrence in comparison to fnb B genes among S. saprophyticus and plasmid may double the rate of same virulence study genes.
DOI: 10.36740/wlek/192862
Institution: Thi Qar University
Language: English
Field: Medicine
Open Access status: bronze
OpenAlex ID: W4404460964
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