Year: 2024
Type: article
Study design: Case Report
Abstract: Toxic epidermal necrolysis (TEN) is one of the most severe drug-induced mucocutaneous reactions, characterised by extensive necrosis and detachment of the epidermis. In majority of cases, the administration of pharmaceutical drugs is thought to be the primary cause of Steven Johnson Syndrome (SJS)/TEN. Erythema, epidermal detachment that manifests as blisters, and denuded skin patches are the defining features of this pathology. In this article, we report a case of a 28- year-old male patient who presented to the emergency with a generalized maculopapular rash all over the body and was taken off the drug immediately and was referred to the burns unit with extensive blisters and skin eruptions all over the body. The patient was treated with intravenous fluids, iv antibiotics, parenteral nutrition and moisture retaining daily dressings. Patient was hospitalised for a period of 2 months and was healed completely without surgical intervention.
Authors: Suhas V Abhyankar, Kurra Vasundhara Devi, Manpreet Juneja, Aravind M Vartak
Language: English
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4404461830