Year: 2024
Type: article
Abstract: T and B lymphocytes exhibit diverse surface receptor repertoires that interact with antigens to communicate and protect the body from foreign invaders.(Haan et al., 2014) Modern methods allows the experimental characterization of the collective identity of the immune cells in tissue samples by sequencing RNA transcripts and cell receptors with scRNA-seq and scTCR-seq / scBCR-seq.Such methods generate high-dimensional data which are analyzed with the aid of dimensional reduction techniques to allow annotation of cell subsets.(Huang et al., 2022)
DOI: 10.21105/joss.06868
Author: Qile Yang
Institution: University of California, Berkeley
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4404482646