Year: 2024
Type: article
Study design: Case Report
Abstract: Congenital cystic eye (CCE) is a rare congenital ocular disease, which has been suggested to be caused by problems with optic vesicle invagination. This is characterized by the formation of intraorbital cystic lesions lined by undifferentiated neuroepithelium. However, cases involving ocular structures with varying degrees of differentiation have also been reported as CCE in humans and animals. In horses, CCE have only been reported as a case presenting as neuroepithelial-lined cysts without the formation of ocular structures. This paper describes large bilateral intraorbital cysts in a 1-day-old horse. The histopathological findings revealed that the cysts were covered by neuroepithelium with formation of the lens, ciliary body, and optic nerve, and it was diagnosed as CCE. This report provides further variations of CCE in horses.
DOI: 10.1292/jvms.24-0285
Authors: Yuto SANO, Chisa MIURA, Yuki KINOSHITA, Miyu KAKIMOTO, Tomonori TSUDA, Kazuya MATSUDA
Institution: Rakuno Gakuen University
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4404493777