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Legionella Pneumonia Undetected by Repeated Urinary Antigen Testing With Ribotest® Legionella

Year: 2024

Type: article

Abstract: This report presents a patient with Legionella pneumonia (LP), initially presented with fever and mild hypoxemia, with subsequent progression to severe pneumonia during hospitalization. Despite multiple negative urinary antigen tests using Ribotest® Legionella, the diagnosis was confirmed via the loop-mediated isothermal amplification method of lower respiratory tract secretions. This case highlights the diagnostic limitations of Ribotest® Legionella and emphasizes the importance of a comprehensive diagnostic strategy, incorporating nucleic acid amplification tests or culture in suspected patients with LP. Early recognition of these diagnostic challenges is critical for optimizing patient outcomes.

Source: Cureus

DOI: 10.7759/cureus.74035

Authors: Yasushi Murakami, Mika Morosawa, Yasuhiro Nozaki, Yoshio Takesue

Language: English

Topic: Legionella and Acanthamoeba research

Subfield: Endocrinology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4404514077

FWCI: 0.273

Cites: 20

Cited by: 1

Related to: 10