Work

Cu(OTf)2-triggered benzotriazole ring cleavage (BtRC) approach for the synthesis of 2-aryl/alkyl benzoxazoles from N-acylbenzotriazoles

Year: 2024

Type: article

Abstract: Cu(OTf)₂ is introduced as a novel reagent for the benzotriazole ring cleavage (BtRC) of N-acylbenzotriazoles (RCOBt), followed by cyclization to the corresponding benzoxazoles.This method exhibits unprecedented efficiency, achieving high yields across a broad substrate scope, including aryl and alkyl derivatives, and is scalable from milligram to gram quantities.

Source: ARKIVOC

DOI: 10.24820/ark.5550190.p012.275

Authors: Rajesh K. Pandey, Anoop S. Singh, Chatrasal S. Rajput, Monika Gupta

Institutions: Babu Banarasi Das University, Jubilant Life Sciences (India)

Language: English

Topic: Structural and Chemical Analysis of Organic and Inorganic Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funder: Centre International de Recherche sur le Cancer

OpenAlex ID: W4404523799

FWCI: 0.141

Cites:

Cited by: 1

Related to: 10