Work

Peripheral antitussives affect temporal features of tracheobronchial coughing in cats

Year: 2024

Type: article

Abstract: In a study on anesthetized cats, peripherally acting antitussives 3-aminopropylphosphinic acid (3APPi) and levodropropizine (Levo) significantly reduced cough number and expiratory efforts, with Levo also reducing inspiratory efforts. Both antitussives altered the cough motor pattern, extending various cough phases. 3APPi shortened diaphragm-abdominal activity overlap, whereas Levo decreased the respiratory rate. These changes contrast with those induced by centrally acting antitussives.

Source: Journal of Applied Physiology

DOI: 10.1152/japplphysiol.00551.2024

Authors: Ivan Poliacek, Marcel Veterník, Lukas Martvon, Michal Simera, Lucia Cibulkova, Zuzana Kotmanova, Denisa Berikova, Donald C. Bolser

Institutions: Comenius University Bratislava, University of Florida

Language: English

Topic: Respiratory and Cough-Related Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Ministerstvo školstva, vedy, výskumu a športu Slovenskej republiky, National Institutes of Health, Agentúra Ministerstva Školstva, Vedy, Výskumu a Športu SR, National Heart, Lung, and Blood Institute

Awards: G1684073081, G4484921860, G5797018547, G9000060342, Central and Peripheral Regulation of Laryngeal Adduction, G970250707

OpenAlex ID: W4404524878

FWCI: 0.254

Cites: 71

Cited by: 1

Related to: 10