Work

Controlling the solid-state and particle properties of a fixed-dose combination co-amorphous system by spray drying

Year: 2024

Type: article

Abstract: Controlling the solid-state stability of co-amorphous systems has been an ongoing challenge in the pharmaceutical field to date. This study demonstrates how spray drying can be used to control the solid-state stability of a co-amorphous system.

Source: RSC Pharmaceutics

DOI: 10.1039/d4pm00257a

Authors: Alice Parkes, Ahmad Ziaee, Emmet O'Reilly

Institutions: University of Limerick, Synthesis and Solid State Pharmaceutical Centre, Cook Medical (Ireland)

Language: English

Topic: Drug Solubulity and Delivery Systems

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

Open Access status: diamond

Funders: Synthesis and Solid State Pharmaceutical Centre, Science Foundation Ireland, Irish Research Council

Awards: G2008096578, G7257840621, SSPC_Phase 2