Work

Severe Coagulopathy Associated With Unintentional Salicylate Intoxication in a Postsurgical Patient

Year: 2024

Type: article

Abstract: Aspirin (acetylsalicylic acid) is administered to treat pericarditis and postpericardiotomy syndrome; however, even therapeutic doses of aspirin can cause chronic intoxication, resulting in severe coagulopathy in patients with chronic kidney disease (CKD). Chronic salicylate intoxication is challenging to diagnose owing to nonspecific symptoms, and treatment is often delayed. Chronic intoxication should be considered in the differential diagnosis of unexplained coagulopathy in patients taking aspirin.

Source: CJC Open

DOI: 10.1016/j.cjco.2024.11.010

Authors: Yuji Kato, Naoto Fukunaga, Takuyo Misumi

Institution: Hyogo Prefectural Amagasaki General Medical Center

Language: English

Topic: Poisoning and overdose treatments

Subfield: Emergency Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,100