Work

“Normal” Glomerular Score Correlates With Outcomes in Antineutrophil Cytoplasmic Autoantibody–Associated Vasculitis With Glomerulonephritis

Year: 2024

Type: article

Abstract: Glomerulonephritis (GN) is a frequent presentation of antineutrophil cytoplasmic antibody–associated vasculitis (AAV),1 and an important factor of morbidity and mortality.2 The kidney biopsy in AAV-GN typically shows necrotizing and crescentic GN. The biopsy may also show sclerosing lesions along with glomeruli that do not show either necrotizing, crescentic, or sclerosing lesions.3 Kidney biopsy is used to determine the prognosis in AAV-GN. The most used system is the Berden classification, which is based on both the extent of glomerular involvement by necrotizing and crescentic lesions and the extent of glomerular scarring.

Source: Kidney International Reports

DOI: 10.1016/j.ekir.2024.11.019

Authors: Marta Casal Moura, Fernando C. Fervenza, Ulrich Specks, Sanjeev Sethi

Institution: Mayo Clinic

Language: English

Topic: Vasculitis and related conditions

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,800