Work

Assessing the mutagenic potential of methyl phenlactonoate 3 and Nijmegen-1 in bacterial reverse mutation assays

Year: 2024

Type: article

Abstract: . After incubating the SL analogs with the tester strains, we observed no significant increase in the number of revertants, with and without the S9 mix, compared to both negative and positive laboratory controls. These results suggest that MP3 and Nijmegen-1 are non-mutagenic according to the bacterial reverse mutation test, supporting their potential as environmentally safe agents for managing Striga populations.

Source: Heliyon

DOI: 10.1016/j.heliyon.2024.e40526

Authors: Muhammad Jamil, Jian You Wang, Kinjal A. Patel, Rajendra M. Nagane, Manish V. Patel, Jalindar Totre, Satish E. Bhoge, Salim Al-Babili

Institution: King Abdullah University of Science and Technology

Language: English

Topic: Carcinogens and Genotoxicity Assessment

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $2,100

Funders: Bill and Melinda Gates Foundation, King Abdullah University of Science and Technology

Award: King Abdullah University of Science and Technology - to significantly increase pearl millet productivity, by providing knowledge and alternative Striga control strategy, which will enhance smallholder...

OpenAlex ID: W4404564573

FWCI:

Cites: 32

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Related to: 10