Work

Chiral clues to lipid identity

Year: 2024

Type: article

Abstract: Oxylipins include octadecanoids, eicosanoids, and docosadecanoids, named for the respective lengths (18, 20, and 22) of their carbon chains. Despite them being evanescent and of low abundance in biological fluids, they exhibit remarkably diverse biological activity which continues to be revealed (1, 2). These pathways have yielded a remarkable number of drug targets, despite meager support from human genetics, including aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs), leukotriene receptor antagonists, and a series of prostanoid receptor (Pr) agonists and antagonists in development.

Source: Journal of Lipid Research

DOI: 10.1016/j.jlr.2024.100710

Authors: Ujjalkumar S. Das, Garret A. FitzGerald

Institution: University of Pennsylvania

Language: English

Topic: Fatty Acid Research and Health

Subfield: Nutrition and Dietetics

Field: Nursing

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,800