Cover Feature: SuFEx‐Functionalized Quinones via Ruthenium‐Catalyzed C−H Alkenylation: A Potential Building Block for Bioactivity Valorization (Chem. Asian J. 22/2024)
Year: 2024
Type: article
Abstract: A direct and modular C-H activation protocol has been employed to develop a novel route for the direct access to ethenesulfonyl-fluorinated 1,4-naphthoquinoidal structures. This culminated in the development of quinone/SuFEx scaffolds with moderate to good yields, utilizing the power of ruthenium catalysis. The identification of prospective trypanocidal prototypes was the result of the evaluation of these new quinoidal/SuFEx hybrids against the trypomastigote forms of Trypanosoma cruzi, the causative agent of Chagas disease. More details can be found in article number e202400757 by Guilherme A. M. Jardim, Eufrânio N. da Silva Júnior, and co-workers.
Source: Chemistry - An Asian Journal
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W4404578008