Work

Use of a Hyperoxic Heated Helium-Oxygen Mixture in an Experimental Model of Cerebral Arterial Air Embolism

Year: 2024

Type: article

Abstract: Arterial gas embolism can result from complications related to medical and surgical procedures, as well as a direct entry of air into the systemic circulation due to the disruption of the alveolar-capillary barrier. Since air in the arterial circulation can lead to organ ischemia, this life-threatening pathology requires prompt intervention. In this study, we demonstrated the effectiveness of using a hyperoxic heated helium-oxygen mixture in cerebral arterial air embolism. Oxygen therapy under normobaric conditions did not affect the outcome of arterial air embolism. A continuous inhalation session for 30 min, or intermittent inhalation sessions 3 times for 5 min each, eliminated foci of ischemic stroke in rats.

Source: Journal Biomed

DOI: 10.33647/2713-0428-20-3e-140-146

Authors: V. A. Palikov, N. B. Pavlov, R. R. Amirov, A. M. Ismailova, S. O. Afanasyeva, E. S. Mikhailov, A. V. Bervinova, I. A. Dyachenko, A. T. Logunov, A. N. Murashev

Institutions: Russian Academy of Sciences, Institute of Bioorganic Chemistry, Institute of Biomedical Problems, Pushchino State Institute of Natural Sciences

Language: English

Topic: Acute Ischemic Stroke Management

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4404578099

FWCI:

Cites: 9

Cited by:

Related to: 10