Work

Next gen liquid biopsy: Comprehensive analysis from a single tube of blood

Year: 2024

Type: article

Abstract: Introduction: In this study, we utilize the high-multiplex protein quantitation capability of Orion, and cell picking capability on CyteFinder, to perform a comprehensive liquid biopsy analysis of whole blood to identify circulating tumor cells (CTCs), large extracellular vesicles (LgEVs), and CTC-white blood cell hybrids; quantify protein biomarker expression on CTCs; perform immune profiling on white blood cells (WBCs); and perform targeted mutation profiling on CTCs and cell-free DNA (cfDNA) from plasma from 7.5 mL of blood.

Source: The Journal of Liquid Biopsy

DOI: 10.1016/j.jlb.2024.100196

Authors: Jon Ladd, Erin Bayer, Brock Bartels, Arista Tischner, Rachel Ponting, Jeff Chamberlain, Arturo B. Ramirez

Language: English

Topic: Cancer Genomics and Diagnostics

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,080

OpenAlex ID: W4404581238

FWCI:

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