Work

Daily versus intermittent iron supplementation among children with iron deficiency anemia: A meta-analysis

Year: 2024

Type: review

Study designs: Systematic Review, Meta-Analysis

Abstract: Objective: This meta-analysis aimed to investigate daily versus intermittent iron supplementation among children. Methods: The author searched the Cochrane Library, PubMed, Medline, and Google Scholar for randomized controlled trials and compared daily versus intermittent iron supplementation. The keywords iron deficiency anemia, iron therapy, daily, twice per week, and once weekly were used. The search was limited to the period January 2012 up to November 2023. The age of participant range from two months to 18 years. Result: Out of the 735 studies, 540 were eligible after removal of duplication, of them, 28 full texts were screened and only 10 studies were included. Daily iron supplementation was better in improving hemoglobin odd ratio, 0.41, 95 CI, 0.38-0.44, Z=26.53, and p-Value <0.001 than intermittent prescription odd ratio, 0.69, 95 CI, 0.67-0.72, Z=49.98, and P-value < 0.001. Conclusion: Daily supplementation increased hemoglobin more compared to weekly or twice/week among children with iron deficiency anemia. Further larger studies assessing tolerance and compliance are needed. doi: https://doi.org/10.12669/pjms.40.11.10344 How to cite this: Alblewi SM. Daily versus intermittent iron supplementation among children with iron deficiency anemia: A meta-analysis. Pak J Med Sci. 2024;40(11):2732-2738. doi: https://doi.org/10.12669/pjms.40.11.10344 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Source: Pakistan Journal of Medical Sciences

DOI: 10.12669/pjms.40.11.10344

Author: Sawsan Mohammed Alblewi

Institution: University of Tabuk

Language: English

Topic: Iron Metabolism and Disorders

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $400