Work

Meta‐Dimethylation of Arenes via Catellani Reaction from Aryl Thianthrenium Salts

Year: 2024

Type: article

Abstract: Here we report the reaction of aryl thianthrenium salts that allows selective functionalization of the meta position of arenes. The combination of a site-selective thianthrenation with a Catellani reaction provides access to 3,5-dimethylated arenes. The developed reaction is complementary to the previously discovered reductive ipso-alkylation of aryl thianthrenium salts and extends the possibilities for late-stage methylation of arenes with a single aryl thianthrenium salt.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.202419472

Authors: Michał Mrozowicz, Sagnik Chatterjee, Markella Aliki Mermigki, Dimitrios A. Pantazis, Tobias Ritter

Institutions: Max-Planck-Institut für Kohlenforschung, RWTH Aachen University

Language: English

Topic: Sulfur-Based Synthesis Techniques

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $5,510

OpenAlex ID: W4404581949

FWCI: 3.53

Cites: 38

Cited by: 25

Related to: 10