Work

Subcomponent analysis of the directional sensitivity of dynamic cerebral autoregulation

Year: 2024

Type: article

Abstract: The directional sensitivity of the cerebral blood velocity response to a sudden change in mean arterial blood pressure (MAP) is mediated by the resistance-area product, without involvement from the cerebral critical closing pressure. The reduced amplitude of MAP spontaneous fluctuations at rest suggests that it is less likely that directional sensitivity has origins in the sympathetic control of cerebral blood vessels, thus generating the need to consider other alternatives.

Source: American Journal of Physiology-Heart and Circulatory Physiology

DOI: 10.1152/ajpheart.00498.2024

Authors: Ronney B. Panerai, Aaron Davies, Abdulaziz Alshehri, Lucy C. Beishon, Jatinder S. Minhas

Institutions: University of Leicester, Glenfield Hospital, NIHR Leicester Biomedical Research Centre, Najran University

Language: English

Topic: Traumatic Brain Injury and Neurovascular Disturbances

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: National Institute for Health and Care Research, Stroke Association, Najran University