Work

Pure Leydig cell tumor of the ovary: a rare presentation of a rare entity in a pregnant patient

Year: 2024

Type: article

Abstract: Aim: Leydig cell tumors (LCT) are rare neoplasms that represent less than 0.1% of all ovarian tumors. This tumor usually presents with signs and symptoms of excess androgen levels. Diagnosis is made based on a combination of history, laboratory findings, imaging techniques and histopathological findings.Case: We present the case of a 35-year-old gravida five para 3+1 pregnant woman with a unilateral ovarian cystic mass that was discovered incidentally during a cesarean section. The cyst measured 9 cm in its maximum dimension. A left oophorectomy was performed after the delivery of an alive male baby. Morphological and immunophenotypic findings were consistent with those of a pure Leydig cell tumor.Conclusion: Leydig cell tumors are uncommon and usually present with hyperandrogenism. The presentation could be polymorphic, ranging from the rapid onset of virilization to being asymptomatic.

Source: Future Science OA

DOI: 10.1080/20565623.2024.2424144

Authors: Anwar Rjoop, Alia Almohtaseb, Daoud O Al Aruri, Dina Hyari, Mohammad Abu shugaer

Institutions: Jordan University of Science and Technology, King Abdullah University Hospital, Jordan University Hospital

Language: English

Topic: Ovarian cancer diagnosis and treatment

Subfield: Reproductive Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,165