Work

Meta‐Dimethylation of Arenes via Catellani Reaction from Aryl Thianthrenium Salts

Year: 2024

Type: article

Abstract: Here we report the reaction of aryl thianthrenium salts that allows selective functionalization of the meta position of arenes. The combination of a site‐selective thianthrenation with a Catellani reaction provides access to 3,5‐dimethylated arenes. The developed reaction is complementary to the previously discovered reductive ipso‐alkylation of aryl thianthrenium salts and extends the possibilities for late‐stage methylation of arenes with a single aryl thianthrenium salt.

Source: Angewandte Chemie

DOI: 10.1002/ange.202419472

Authors: Michał Mrozowicz, Sagnik Chatterjee, Markella Aliki Mermigki, Dimitrios A. Pantazis, Tobias Ritter

Institutions: Max-Planck-Institut für Kohlenforschung, RWTH Aachen University

Language: English

Topic: Sulfur-Based Synthesis Techniques

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $5,250

OpenAlex ID: W4404592800

FWCI: 0.141

Cites: 38

Cited by: 1

Related to: 10