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Directed Evolution of an Adenylation Domain Alters Substrate Specificity and Generates a New Catechol Siderophore in Escherichia coli

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Year: 2024
Type: article
Source: Biochemistry
DOI: 10.1021/acs.biochem.4c00499
Authors: Erin Conley, Caryn S. Wadler, Bailey A. Bell, Ivy Lucier, Caroline Haynie, Sophie Eldred, Valerie Nguyen, Tim S. Bugni, Michael G. Thomas
Institutions: University of Wisconsin–Madison, Great Lakes Bioenergy Research Center
Language: English

Topic: Microbial Natural Products and Biosynthesis
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences

Open Access status: closed

Funders: Wisconsin Alumni Research Foundation, University of Wisconsin-Madison, National Institute of Food and Agriculture, Division of Molecular and Cellular Biosciences, Biological and Environmental Research
Awards: G1648283888, G5015097314, G5125187766
OpenAlex ID: W4404592925
FWCI: 2.118
Cites: 53
Cited by: 9
Related to: 10
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