Year: 2024
Type: article
Abstract: Neuroleptic malignant syndrome (NMS) is a rare but life-threatening neurological emergency associated with the idiosyncratic reaction to dopamine-receptor antagonist medications or with rapid withdrawal of dopaminergic medications. While uncommon, this condition can mimic various other acute conditions presenting with acute dysautonomia, fever, and altered mental status, which can lead to delayed recognition and increased morbidity such as residual catatonia, parkinsonism, renal, or cardiopulmonary complications. Therefore, high vigilance, early recognition, and prompt treatment are necessary. In this review article, we aim to elaborate the pathophysiology, clinical features, and comprehensive management of NMS, with a special focus on its various mimicking conditions.
Authors: Adel Ekladious, Ritesh Bhandari, Muhammad M Javaid, Pratima Gurung
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4404596781