Work

Intestinal Pseudo-Obstruction After Vincristine Use

Year: 2024

Type: article

Abstract: A 73-year-old man presented with nausea, abdominal discomfort, and distention persisting for the past five days. He had previously been diagnosed with stage III peripheral CD4+ T cell lymphoma and had initiated chemotherapy comprising vincristine two weeks prior to presentation. An evaluation revealed diffuse colon distention and pneumatosis intestinalis without mechanical obstruction, consistent with acute colonic pseudo-obstruction. The patient underwent surgical intervention and was subsequently admitted to the Intensive Care Unit due to distributive shock. Vincristine-induced ileus followed by intestinal pseudo-obstruction was suspected to be the underlying cause after excluding alternative causative factors.

Source: Cureus

DOI: 10.7759/cureus.74213

Authors: Miguel Monteiro, Beatriz Castanheira, Elsa Meireles, Nuno Príncipe, José-Artur Paiva

Institutions: Unidade Local de Saúde do Tâmega e Sousa, Unidade Local de Saúde de Almada-Seixal, Unidade Local de Saúde de Entre Douro e Vouga, Hospital de São João, Universidade do Porto

Language: English

Topic: Gastrointestinal motility and disorders

Subfield: Gastroenterology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4404612762