Work

Mucus-on-a-chip: investigating the barrier properties of mucus with organic bioelectronics

Year: 2024

Type: article

Abstract: model of a GI mucus-on-a-chip has been developed with integrated electronics to monitor the barrier properties of mucus hydrogels. Its application for investigating the effect of drugs and biofilm formation on the mucus structure is validated using rheological techniques, confocal microscopy and electrochemical impedance spectroscopy (EIS).

Source: Journal of Materials Chemistry B

DOI: 10.1039/d4tb01351d

Authors: Reece McCoy, Kaixin Wang, Jeremy Treiber, Ying Fu, George G. Malliaras, Alberto Salleo, Róisín M. Owens

Institutions: University of Cambridge, Stanford University, University of Strathclyde

Language: English

Topic: Hydrogels: synthesis, properties, applications

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Funders: National Science Foundation, Henry Royce Institute, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Engineering and Physical Sciences Research Council, Division of Electrical, Communications and Cyber Systems, Air Force Office of Scientific Research

Awards: G111330326, NNCI: nano@stanford, EPSRC Centre for Doctoral Training in Integrated Functional Nano (i4Nano), G355476329, G4048582220, G4089419421, G4991665947, G504327055, G708391930, G715292007, Sir Henry Royce Institute - Cambridge Equipment, G7594288067, G8065195062, Sir Henry Royce InsStitute - recurrent grant

OpenAlex ID: W4404613619

FWCI: 1.058

Cites: 50

Cited by: 10

Related to: 10