Work

Safety profile of pulsed field ablation regarding phrenic nerve function

Year: 2024

Type: article

Abstract: We read with great interest the comprehensive review by Sugrue and colleagues.1 Pulsed field ablation (PFA) is a promising, nonthermal energy allowing efficient pulmonary vein isolation during atrial fibrillation catheter ablation. However, uncertainties persist regarding the impact of PFA on right phrenic nerve (PN) function, with a subsequent risk of PN stunning (ie, transient) or palsy (ie, persistent). Indeed, data from the recently published MANIFEST-17K (Multi-National Survey on the Safety of the Post-Approval Clinical Use of Pulsed Field Ablation in 17,000+ Patients) registry found a low incidence (0.06%) of PN palsy,2 but such a complication might have been overlooked by the retrospective design of the study and the absence of systematic PN function monitoring during PFA procedures.

Source: Heart Rhythm O2

DOI: 10.1016/j.hroo.2024.11.013

Authors: Pierre Ollitrault, Corentin Chaumont, Jonaz Font, Laure Champ-Rigot, Frédéric Anselme, Paul Milliez

Institutions: Centre Hospitalier Universitaire de Caen Normandie, Université de Caen Normandie, Centre Hospitalier Universitaire de Rouen

Language: English

Topic: Atrial Fibrillation Management and Outcomes

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,150