Case report: The use of Venovenous Extracorporeal Membrane Oxygenation in the Treatment of Acute Respiratory Distress Syndrome in Severe Leptospirosis
Year: 2024
Type: article
Study design: Case Report
Abstract: Leptospirosis is a globally distributed zoonosis with a clinical spectrum ranging from mild febrile illness to life-threatening disease, that can result in acute kidney injury (AKI) and severe pulmonary complications such as alveolar hemorrhage and acute respiratory distress syndrome (ARDS). We present the case of a 20-year-old man with fever and respiratory distress, diagnosed with ARDS and AKI. Venovenous (VV), extracorporeal membrane oxygenation (ECMO) and sustained low-efficiency daily dialysis (SLED) were initiated. The patient showed significant respiratory improvement after eight days and renal recovery after seventeen days. Leptospirosis serological conversion confirmed the diagnosis. This case highlights the potential of VV ECMO as an effective supportive therapy in severe respiratory failure secondary to leptospirosis. Early recognition and aggressive management, including ECMO and daily dialysis, may enhance outcomes in severe pulmonary leptospirosis.
Authors: Fernando de Oliveira e Silva Neto, Renan Gomes Mendes Diniz, Gabriel Cavalcante Lima Chagas, Helen Melo Oliveira Felix, Ana Larissa Pedrosa Ximenes, Bráulio Matias de Carvalho, Fátima Rosane de Almeida Oliveira, Daniel Francisco de Mendonça Trompieri, Juan Alberto Casquillo Meija, Lucia da Conceição Andrade, Elizabeth de Francesco Daher
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4404626289