Work

Epstein-Barr Virus-Associated Smooth Muscle Tumor in the Liver Post Kidney Transplant: A Case Report

Year: 2024

Type: article

Abstract: Epstein-Barr virus (EBV) is one of the most common causes of infection from the herpes virus family which also possesses oncogenic potential. EBV-associated smooth muscle tumors (EBV-SMT) are often found in the CNS but here we present the case of a 50-year-old woman with EBV-SMT in the liver. This patient had a kidney transplant in 2009 and had been undergoing immunosuppressive therapy to support her transplant. Subsequent imaging found a liver mass which was not seen on previous imaging. The biopsy revealed an EBV-SMT. The exact pathophysiology of EBV-SMT is not clear though it is believed to involve the reactivation of latent infection through mTOR pathways. Treatment of such masses includes reducing immunomodulating pharmacotherapy though no established management guidelines exist.

Source: Cureus

DOI: 10.7759/cureus.74441

Authors: Zeshan R Ali, Burak Sevim, Ramy Shoela

Institution: Saint Louis University

Language: English

Topic: Viral-associated cancers and disorders

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4404684176