Year: 2024
Type: article
Abstract: Cancer is a complex disease influenced by various factors, including DNA damage, growth signals, and inflammation. Although inflammation has commonly not been considered carcinogenic, increasing evidence indicates its substantial involvement in the onset and progression of cancer, especially in the presence of chronic microbial infections. This review thoroughly analyzes the complex relationship between cancer, health, and inflammation by introducing pathological and physiological features of inflammation. The study explores the various factors that might enhance inflammation, including infections and para-inflammation caused by tissue stress. It will also explore the changing comprehension of microorganisms about health and illness, clarifying their possible influence on the development of several malignancies, including colon, pancreatic, gastric, and prostate cancers. In addition, the study emphasizes the development of new therapy approaches that specifically target chronic inflammations and their associated cancers. This review seeks to enhance the comprehension of the intricate correlation between cancer, inflammation, and human health by combining existing research.
Authors: Sikandar Naseer, Gulnaz Tasleem, Bareera Zahoor, Bisma Hadi, Amna Amin, Alishba Hadi
Institution: Islamia University of Bahawalpur
Language: English
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4404724866