Work

A simple blinding index for randomized controlled trials

Year: 2024

Type: article

Abstract: Blinding is an essential part of many randomized controlled trials. However, its quality is usually not checked, and when it is, common measures are the James index and/or the Bang index. In the present paper we discuss these two indices, providing examples demonstrating their considerable weaknesses and limitations, and propose an alternative method for measuring blinding. We argue that this new approach has a number of advantages. We also provide an R-package for computing our blinding index.

Source: Contemporary Clinical Trials Communications

DOI: 10.1016/j.conctc.2024.101393

Authors: David Petroff, Miroslav Bacak, Nikolaos Dagres, Patrick Dilk, Rolf Wachter

Institutions: Leipzig University, Deutsches Herzzentrum der Charité, Leipzig Heart Institute, University Hospital Leipzig

Language: English

Topic: Statistical Methods in Clinical Trials

Subfield: Statistics and Probability

Field: Mathematics

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $2,350

OpenAlex ID: W4404726246

FWCI: 3.993

Cites: 19

Cited by: 11

Related to: 10