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A New Era for Peptide Therapeutics: Innovations, Challenges, and Future Directions

Year: 2024

Type: article

Abstract: Peptide drugs are experiencing a renaissance driven by technological breakthroughs and the success of recent blockbuster drugs. A versatile peptide chemistry toolbox, modern synthesis techniques, and powerful discovery platforms are addressing many inherent roadblocks in peptide drug discovery and development allowing complex diseases to be targeted with high specificity and efficacy. As we enter a new era, peptide drugs are well suited to pursue inherently challenging, underrepresented targets and provide innovative treatment options.

Source: CHIMIA International Journal for Chemistry

DOI: 10.2533/chimia.2024.783

Author: Nathalie M. Grob

Institution: ETH Zurich

Language: English

Topic: Chemical Synthesis and Analysis

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: National Science Foundation, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung