Work

New bioactive mono-acyl glycerol ester from the Red Sea marine coral Sclerophytum levi

Year: 2024

Type: article

Abstract: The chemical examination of the soft coral Sclerophytum levi collected from the Red Sea led to isolation and structurally elucidation of a new mono- acyl glycerol ester, [(2R)-2,3-dihydroxypropyl] (2R)-2-hydroxypentadecanoate (1), along with myristyl palmitate (2), (Z)-2-(9-octadecenyloxy) ethanol (3), 24-methylene cholesterol (4) and 23-demethylgorgosterol (5). The chemical composition of the isolated metabolites was determined via optimised spectroscopic analysis, including 1D and 2D NMR analyses. The new mono alkyl glycerate (m-AG) showed moderate antimicrobial activity against Staphylococcus aureus, Proteus vulgaris, Escherichia coli and Candida albicans microbial strains using agar well diffusion method and recorded a weak in vitro cytotoxic and antioxidant activities.

Source: Natural Product Research

DOI: 10.1080/14786419.2024.2432614

Authors: Basma H. Farouk, Asmaa M. Abdel-Tawab, Mohamed E. Mostafa, Fawzia Z. El-Ablack, El Sayed A. E. Hamed, Seif-Eldin N. Ayyad

Institutions: Damietta University, National Institute of Oceanography and Fisheries, National Research Centre, Agricultural Research Center, Viện Bảo vệ thực vật

Language: English

Topic: Marine Sponges and Natural Products

Subfield: Biotechnology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W4404740913

FWCI:

Cites: 37

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Related to: 10