Correction of B0-related distortions in diffusion-weighted images of malignant and normal cervical tissue
Year: 2024
Type: erratum
Abstract: Motivation: DWI in cervical cancer evaluation suffers from distortions, especially pronounced by intestinal gas, potentially impeding lesion detection/delineation. Goal(s): To evaluate a combined prospective-retrospective distortion reduction approach, based on distortion correction of female pelvic DWI acquired with reduced-FOV. Approach: Two correction methods, RPG and Topup, were applied on images from cervical cancer patients and volunteers. Distortion correction performance was evaluated by the concordance between tumour/cervix borders in images before and after correction. Results: Topup outperformed RPG, with statistically significant but modest improvements of initially small distortions resulting from the reduced-FOV acquisition. Occasional correction failures and limitations in the proton density correction warrant alternative approaches. Impact: Topup distortion correction, commonly used for brain studies, shows statistically significant but modest improvements in female pelvic reduced-FOV DWI. Despite indications of clinical utility, limited improvements and occasional correction failures suggest alternative approaches and prospective distortion reduction as potential strategies.
DOI: 10.58530/2024/2581
Authors: Elin Lundström, Ana Rodríguez-Soto, Christopher Conlin, Stephane Loubrie, Stephan Jordan, Sheida Ebrahimi, Alexandra Besser, Alexandra Schlein, Marianne Hom-Tedla, Cheryl Saenz, Shira Varon, Michael McHale, Michael Hahn, Elisabeth Hedlund, Björg Jónsdóttir, Katarzyna Kozar, Joshua Kuperman, Tyler Seibert, Anthoula Koliadi, Per Liss, Anders Dale, Rebecca Rakow-Penner
Language: English
Topic: MRI in cancer diagnosis
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4404743703