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Fat-corrected non-Gaussian diffusion MRI in a non-alcoholic fatty liver disease: diagnostic performance for liver fibrosis

Year: 2024

Type: conference-paper

Abstract: Motivation: In nonalcoholic fatty liver disease (NAFLD), hepatic fibrosis is strongly associated with patient survival. Diffusion MRI has been proposed to assess liver fibrosis, but this evaluation is hampered in hepatic steatosis. Goal(s): Our goal was to evaluate the diagnostic performance of non-Gaussian diffusion MRI in assessing liver fibrosis in 250 patients with NAFLD. Approach: We developed a method to calculate the non-Gaussian diffusion coefficient, based on non-linear regression and fat correction. Results: With this corrected diffusion method, NAFLD patients with liver fibrosis could be differentiated from patients without it. Impact: With this corrected diffusion method, NAFLD patients with liver fibrosis could be differentiated from patients without it.

Source: Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition

DOI: 10.58530/2024/5183

Authors: omaima said, Sabrina Doblas, Gwenaël Pagé, Dominique Valla, Valérie Paradis, Bernard Van Beers, Philippe Garteiser

Institutions: Centre de Recherche sur l'Inflammation, Hôpital Beaujon

Language: English

Topic: Liver Disease Diagnosis and Treatment

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4404744276

FWCI:

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