Work

Exploring connectivity and microstructural recovery following detoxification in individuals suffering from Alcohol Use Disorder

Year: 2024

Type: conference-paper

Abstract: Motivation: Alcohol use disorder (AUD) is a widely spread disorder responsible for 6% of global mortality. Alcohol affects a substantial portion of the population in various aspects and part of these changes may be related to brain modifications. Goal(s): To identify the effects of alcohol withdrawal on the brain and their link with symptom improvement. Approach: Combination of connectivity matrices and microstructural models based on diffusion MRI tested during withdrawal period. Results: The study of global brain connectivity revealed six connections, four of which also showed microstructure changes during withdrawal that were beneficial for recovery in areas heavily affected by increased alcohol consumption. Impact: We presented an exploratory way to evaluate the effects of short-term withdrawal using connectivity and microstructural models based on diffusion MRI. It revealed four brain connections that deserve to be studied in greater depth in the case of this pathology.

Source: Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition

DOI: 10.58530/2024/1727

Authors: Manon Dausort, Nicolas Delinte, Melissa Salavrakos, Laurence Dricot, Philippe de Timary, Benoît Macq

Language: English

Topic: Advanced Neuroimaging Techniques and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4404745530

FWCI:

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