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Assessment of structural-functional integration impact on connectivity abnormalities in glioma patients

Year: 2024

Type: conference-paper

Abstract: Motivation: Brain networks glioma’s disruption was often explored through separate examinations of structural and functional connectivity. However, there were limited efforts in glioma research to investigate the interplay between structure-function and how this connection might influence our comprehension. Goal(s): Can integrating structural and functional connectivity aid understanding the alterations’ neurobiological foundation in brain networks caused by glioma?Approach: The study design involves standard diffusion MR and rs-fMRI preprocessing, statistical methods including Pearson and Spearman correlation and Euclidean distance computation. Results: This study underscores the significance of examining structure-function integration, where both microstructure and function play crucial roles in relation to white matter integrity. Impact: Glioma, the primary brain tumor, affects both structural and functional connectivity. Understanding alterations in structure-function integration and connection with single-modalities, may be of highest significance for a more comprehensive explanation of compensatory mechanisms induced by glioma and its clinical progression.

Source: Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition

DOI: 10.58530/2024/0373

Authors: Maria Colpo, Erica Silvestri, Diego Cecchin, Maurizio Corbetta, Alessandra Bertoldo

Language: English

Topic: Advanced Neuroimaging Techniques and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4404749032

FWCI:

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