Year: 2020
Type: article
Abstract: Simulation involves predicting the responses of a physical system. In this article, we simulate opto-acoustic signals generated in a 3-D volume due to the absorption of an optical pulse. A separable computational model is developed, which splits processing into two steps, permitting an order-of-magnitude improvement in computational efficiency over a nonseparable model. The simulated signals represent acoustic waves, measured by a probe with a linear transducer array, in a rotated and translated coordinate frame. Light is delivered by an optical source that moves with the probe's frame. Spatiotemporal impulse response for rectangular-element transducer geometry is derived using Green's function solution to the acoustic wave equation. The approach permits fast and accurate simulation for a probe with an arbitrary trajectory, which is useful for modeling freehand acquisitions. For a 3-D volume of n3voxels, computation is accelerated by a factor of n. This may potentially have application in opto-acoustic imaging, where clinicians visualize structural and functional features of biological tissue for assessment of cancer and other diseases.
Authors: Jason Zalev, Michael C. Kolios
Institution: Toronto Metropolitan University
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W3100906515