Work

Locoregional therapy of oligometastatic breast cancer

Year: 2024

Type: article

Abstract: Summary Oligometastastic disease has been defined as not more than five metastases found in radiological workup within not more than two different distant organs of the body [1]. Starting in 1995, several authors claimed that local treatment, especially radiotherapy, may have a positive impact on oligometastatic patients. However, prospective trials demonstrated that local therapy of nonsymptomatic metastases should not be routinely offered as there is no survival benefit. Surgical resection of primary breast cancer in synchronous stage IV disease should also not be offered. However, there is a window of opportunity for men and women with synchronous oligometastatic disease where a true R0 resection by treating metastases as well as the primary cancer may be achieved. These cases need to be discussed within a multidisciplinary team (MDT) conference and should be included in new trials.

Source: memo - Magazine of European Medical Oncology

DOI: 10.1007/s12254-024-01008-1

Author: Florian Fitzal

Institutions: Hanusch Hospital, Medical University of Vienna

Language: English

Topic: Breast Cancer Treatment Studies

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,590