Year: 2024
Type: article
Abstract: The precise control of complex reactions is critical for biological processes, yet our inability to design for specific outcomes limits the development of synthetic analogs. Here, we leverage differentiable simulators to design nontrivial reaction pathways in colloidal assemblies. By optimizing over external structures, we achieve controlled disassembly and particle release from colloidal shells. Lastly, we characterize the role of configurational entropy in the structure via both forward calculations and optimization, inspiring new parameterizations of designed colloidal reactions.
Source: Physical Review Letters
Institutions: Harvard University, Simons Foundation, New York University
Language: English
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W4404758044